We welcome new graduate student Rochelle Lai to the lab. Rochelle is a first year student in the UCLA MCIP Program. After less than a week she's already blowing things up the lab!
Congratulations to Liz on being award a highly prestigious American Heart Association Established Investigator Award! Former Alumni from UCLA include Drs. Peter Edwards, Jake Lusis, Karen Reue, and DOM Chair Dale Abel. She's in excellent company!
After a GOLIATH amount of work, we are super exicted to see our publication in Circulation Research describing a new horizon for LDLR regulation. We discover the molecular mechanism underlying previously observed genome-wide associations in humans in the RNF130 locus. We found that RNF130, a unique membrane-bound E3 ubiquitin ligase, regulates LDLR abundance and availability at the plasma membrane. Also, our artwork was selected for the cover! Check it out here !
Excited for the first publication of 2023 - a review on GM-CSF antibodies in Pulmonary Alveolar Proteinosis - read all about it here !
The ETV Lab is celebrating its 10 year anniversary this year. The lab was established in January 2013 and we are excited for the next 10 years!
The 4th Annual Deck the Lab contest is here! Check out this year's entries and winners!
Excited to receive the NOA for an MPI R01 to study the gut-liver axis in cardiovascular disease!
The ETV lab represented BIG TIME at the 2022 UCLA Department of Medicine Research Day. Congratulations to postdoc Dr. Kelsey Jarrett, and graduate students Gabriella Rubert, Alvin Chan, and Emily Smith on sweeping the awards! Also a shoutout to undergradute researcher Min Jin Kim on presenting her research.
Congratulations to PhD Candidate Gabriella Rubert on successfully passing her Orals!
The lab attended the 2022 UCLA Cardiovascular Theme Symposium. What a fun day! And congratulations to postdoc Dr. Kelsey Jarrett on being awarded 2nd place in the poster competition!
Congratulations to PhD Candidate Emily Smith on successfully passing her Oral Qualifying Exam!
We are on a roll! Congratulations to our newest postdoc Heidi Schmidt who received a Postdoctoral Fellowship in the Vascular Biology T32 Program!
Three is the magic number! Congratulations to graduate student Emily Smith who received a Predoctoral Fellowship in the Cellular and Molecular Biology T32 Program!
Congratulations to undergraduate research Rodrigo Balthazar Nunez on being selected for a summer internship!
The ETV lab spent the day at the beach enjoying the SoCal Sunshine!
Tom presents some new and exciting science at the 2022 Gordon Research Conference on Lipids and Lipoproteins - one of our favorite meetings!
Congratulations to graduate student Emily Smith who was selected for the prestigious Whitcome Fellowship!
We are super proud of undergraduate research Maria Taveras for being selected as a Dean's Prize Winner!
We are excited with our new lab jackets, courtesy of the Department of Biological Chemistry and UCLA...don't we look fancy!
This month we said farewell to our first ever postdoc, Dr. Bethan Clifford. Bethan is moving on to bigger and greater things at Amgen, but at least she is not far away and is still available for happy hours! We wish her every success in her new endeavour!
Congratulations to graduate student Gabriella Rubert who received a Predoctoral Fellowship in the Genomics and Transcriptomics T32 Program!
We are excited to welcome our new postdoc Heidi to the ETV Lab! Heidi completed her PhD at the University of Pittsburgh and we are glad she moved from the East Coast to the Best Coast!
Congratulations to Dr. Bethan Clifford on being selected as the 2021-2022 George J. Popjak Scholar for Outstanding contributions to the field of Atherosclerosis Research! This is especially meaningful as both Tom and Liz are past winners of this award. Huge congratulations Bethan, we are very proud of you!
At the beginning of this month we said goodbye to postdoc Dr. Leslie Sedgeman, who has taken a position at LA startup Nuanced Health. We are excited to see what she gets up to!
What a way to round out 2021. Tom is named the Home Area Director for the MBIDP Gene Regulation, Epigenetics and Transcriptomics graduate home area in the UCLA Graduate Programs in Bioscience! Congratulations Tom!
We continued our annual tradition of our Deck The Halls Lab Contest. This year we shook things up a little and challenged lab members to create a decoration that we can hang on our new Lab Christmas Tree. Check out our tree and this years' entries, runners up and overall winner!
Celebrating the Big Boss birthday in traditional ETV style. CAKE!
We got ourselves a new lab profile pic.
Tom presents some of the lab's newest and greatest research at the UCLA Cardiovascular Theme Symposium, our first in-person event in almost 2 years!
Now that things are opening up a little, the lab got out for some much needed fresh air and a bit of a break from the bench!
We are super happy and exicted that Gabriella Rubert has decided to join the lab as a Ph.D. student! Meet Gabriella here .
We are VERY exicted that our studies on FXR agonists protecting against fatty liver disease have been accepted for publication in Cell Metabolism. Postdoc Bethan led these studies in collaboration with Leslie and Kelsey. Five years is a long time coming!
We are exicted that Emily Peluso Smith has decided to join the lab as a Ph.D. student! Learn more about Emily here .
Excited to get the Notice of Award for (can you believe it) the first MPI R01 for Liz and Tom!
Congratulations to postdoc Maddy Brearley-Sholto on being awarded an AHA Postdoctoral Fellowship!
We're WRAPPED up! Excited to see our first publication from our collaboration with the Pellegrini Lab! Here our collaborators report the ultrastructural organization and dynamics of the inter-organellar contact established by sheets of curved rough endoplasmic reticulum closed wrapped around the mitochondria (wrappER). Check out the awesome videos and images demonstrating liver wrappER-mitochondria contacts participate in VLDL biology.
Another publication with our Australian Collaborators! Great to see this continuing despite the global pandemic!
Congratulations to ETV Alumni Tim Yu on another paper published!
Excitement in the lab to get the first shots of our COVID-19 vaccines!
Congratulations to the lab for their Christmas Decoration entries! We were selected as one of the winners of Addgene's #DeckTheLab contest! Can't wait to see what our prizes are!
Congratulations to Research Fellow Alvin for his latest research on dietary trends in the rare pediatric disorder glucose galactose malabsorption .
We are kicking off 2021 in style with the release of our new lab logos!
Another first for the year, the lab hosted a virtual Christmas Party, complete with cookie decorating, mocktails, and our famous Christmas Decoration Competition!
Tom is promoted to Associate Professor, with Tenure! What an amazing achievement!
We are excited to share our latest research defining the role for the E3 ubiquitin ligase GOLIATH in regulating plasma LDL cholesterol and LDL receptor availability.
Liz, Tom, and Olivia welcome Baby Leo!!
Postdoc Leslie is awarded one of the first iCMB T32 postdoctoral training grants, bridging bioengineering and biomedical science! Well done Leslie!
In the lab's first ever Zoom Ph.D. Defense, MCIP graduate student Elinor successfully defended her thesis! Congratulations Elinor, we are so proud of you!
Postdoc Leslie welcomes baby Sophia to the world! Congratulations Leslie, Carl, and Lucky the dog!
We are very pleased and excited to welcome Gabriella Rupert as a Rotation student to Team CRISPR. Gabriella will working on designing guide RNAs to some of our newly identified metabolism targets.
We are excited to welcome Alvin Chan as a Research Fellow in Pediatrict GI. Alvin will be working on all things related to bile acids and absorption! Get to know Alvin here .
Postdoc Kelsey succesfully renews her T32 Vascular Biology Training Grant for another year. Well done Kelsey!
We are super thankful to be able to re-open the lab as part of UCLA's research ramp-up. Even if we are capped at 25% capacity we are back at full speed!
As COVID-19 continues to impact our research, we are happy to welcome rotation student Kelly Kennewick to the lab for a virtual rotation. Kelly is part of the IMMP home area in the GBP at UCLA and will be working with Liz on analyzing lipidomic and FACS data in mice with disrupted lipid and immune homeostasis.
This time we said Goodbye to Li, who is going back to NorCal to work in Industry. We didn't get to have a proper farewell thanks to Pandemic Restrictions and the Safer-at-Home order in Los Angeles, but we wish her all the best!
Along with many other labs and research campuses across the country, we made the difficult decision to shut down our lab in mid-March as COVID-19 began to rage and Los Angeles issued an emergency Safer-at-Home order.
We are desperately sad to be saying Au Revoir to our favorite baker/technician extraordinaire, Pauline, who is returning to her native France. The lab took to her beloved trails for a farewell hike, and we couldn't let her leave without baking just one more delicious cake!
We are delighted to welcome Super-Tech Michelle Steel to Team ETV! Go check out her bio here .
Yet another publication, this time from undergrad Tim's previous lab. This is Tim's first first author publication and preprint where they built and tested 8269 variations of the classic lac promoter where we reposition and tune the strengths of binding sites. This study shows new interactions between binding sites and how to build theoretically optimal inducible promoters. Read this cool story about promoter architecture here .
What a way to ring in 2020 with not one, but two papers accepted from the lab! First, we performed silencing of microRNA-144 in pre-clinical models of atherosclerosis. Second, in collaboration with Jan Kornfeld, we discoverd a MAFG-lncRNA axis that links nutrient abundance and hepatic glucose metabolism.
The lab were allowed to venture outside for the afternoon for our annual all-you-can-eat Brazilian Churrascaria BBQ at Fogo de Chao! Post-prandial studies followed of course!
The lab celebrated Thanskgiving with their annual Friendsgiving meal!
We are delighted and excited to welcome Angela Sun and Yifan Wang (Frank) to the lab for their fall rotation! Angela will be working with Liz on lipids and immune cells. Frank will be working with Tom and Kelsey following up on PSMD9, which we identified using systems biology tools.
Today we celebrated postdoc Bethan and Kelsey's big summer birthdays!
Our undergraduate Rachel who has been working over the summer as part of the CARE summer research program, presented her research! Well done Rachel!
Today we said farewell to Postdoc Jenny Link, who is starting a faculty position at Whittier College. We will miss you and are very proud of you Jenny! Good luck in your next adventure!
Summer BIG students Tyler and Vivan present their work. Lots of fun talking science!
We are delighted and excited to welcome Tyler Laws and Vivian Iloabuchi, our Summer Bruins In Genomics (BIG) students to the lab!
We were sad to say goodbye to Elizabeth Vanderwall at the end of this month. Elizabeth is moving home to Seatle before embarking on the next chapter of her adventures and applying to Grad School.
The lab made some furry new friends in what was possibly the best. day. in. lab. ever!
The lab made sure to document #nationalselfieday by cramming everyone into a very small space!
Liz gives a talk at the Gordon Research Conference on Atherosclerosis at Sunday River, Newry, ME!
Liz gives Medicine Grand Rounds with Dr. Tisha Wang discussing the progress they have made working on Pulmonary Alveolar Proteinosis!
Gloria, who has been in charge of our animal colony for several years, is promoted at UCLA. We celebrated with another delicious cake from Chef Morand! We wish Gloria all the best and we will miss her terribly!
We were visited by 64 middle school students from LAUSD Stephen M. White Middle School and their teach, former Tarling-Vallim Alum, Mrs. Tammy Kim!
Our bioinformatic undergrad Timothy Yu presented a poster on his exciting analysis of lipidomic profiling. Well done Tim!
Congratulations to Postdoc Kelsey Jarrett on being awarded the UCLA Vascular Biology T32 postdoctoral fellowship! Well done Kelsey!
Congratulations to Tom and Dr. Peter Edwards on being awarded an NIH MPI R01 to study FXR and liver lipid metabolism!
In collaboration with colleagues at the Baker Heart and Diabetes Institute, in Mebourne Australia, we performed a systems genetics analysis of mammalian lipid metabolism. Check out this report for more information.
In collaboration with the Pamir Lab at Oregon Health and Sciences University we performed a large scale genetic study of the HDL proteome.
Another Christmas, another lab all-you-can-eat adventure. Thank you Fogo De Chao!
This month we welcome new postdoc Leslie Sedgeman to the lab! Leslie did her PhD at Venderbilt University in the lab of Kasey Vickers.
This month we welcome our new Lab Assistant Elizabeth Vanderwall! Elizabeth was an undergrad at UCLA and worked in the lab through the summer Bruins In Genomics program. Now she has joined the lab full-time!
We published some of our latest findings in Nature Communications on the use of Statins as a novel pharmacotherapy in the rare lung disease, Pulmonary Alveolar Proteinsis and had a featured news article.
Liz was promoted to Associate Professor! Congrats Prof!
Want to know more about the research that led to Liz's Irvine H. Page Young Investigator Research Award? Well, check out the official post-award interview:
Liz wins the Irvine H. Page Young Investigator Research Award at Vascular Discovery: From Genes to Medicine 2018 Scientific Sessions!
Happy Birthday to the #OG boss, Dr. Peter Edwards!
The lab recently got a big news: Joan got accepted in Graduate School and will soon leave to the University of Utah to start their graduate program. While it's a bit of a bummer for us to lose Joan, we couldn't be more happier for her, she worked hard and her hard work paid off! Congrats Joan! And yes, of course we had to party for the occasion, another fun night in Brazilian "All you can eat" pizza territory.
Hey, look what just arrived! The lab is now equipped with a brand new mass spectrometer. 2018 is going to be a data-driven year for sure!
Christmas time is always a good excuse for a lab all-you-can-eat excursion. Thanks Fogo De Chao for hosting us!
Is it Christmas yet? Congrats to the lab for the fantastic work that led to winning the Paul Dudley White award for highest scoring abstract at the AHA 2017 (Anaheim).
Did we tell you that each time the Dashew Center for International Students and Scholars is holding a World Café event we never miss a chance to sample caffeinated drinks from all over the world? Well, guess what, there is even a video to prove it, featuring Pauline, Elinor and Joan!
And just like that, it's time to eat another cake again, this time in honor to Jenny: Happy Birthday!
Congrats to our own Bethan for winning the UCLA Cardiovascular Theme Research Day Poster Award! #GoBethan
Adam and Elizabeth did a terrific job presenting their work at the UCLA Undergraduate Research Day. Thanks to everyone who came by to ask questions!
We published a novel posttranscriptional mechanism for regulation of bile acid metabolism. A great excuse to gather the lab for another all-you-can-eat pizza party!
Look at those two, always upon us and always playing together! But when they meet, it's always a good enough reason to do a short break. Alright, now back to work, science awaits!
Liz was awarded the David Williams Lectureship at the 2017 Kern Lipid Conference.
Liz and Bethan run the The San Francisco Marathon and Joan completes her first half marathon!
It's time for Sophia to embark on her European journey. We are sad to see her leave but at least we got another cake by Chef Pauline. Thanks for everything Sophia, we wish you the best in your new adventure!
We have the grand opening of our newest Tissue Culture suite (aka Pauline's room!). After a long slog, we are finally open for business.
Liz receives her first NIH R01 grant from the NHLBI.
Pauline just completed her first 50K trail race at the Gorges Waterfall 50k!
We welcome Sophia Franco-Castillo as our newest lab member. Sophia was an undergraduate in the lab, and graduated UCLA. She has now joined the lab full time!
We published our latest findings on pulmonary surfactant homeostasis, and had a featured news article in ASBMB.
Tom receives his second NIH R01 grant from the NIDDK. Just another excuse for the lab to go to all you can eat pizza to celebrate.
We officially welcome Pauline Morand to the lab.
Jenny Link, PhD, a post-doctoral fellow from UCLA joins the Tarling-Vallim lab. Welcome Jenny!
Lab Christmas party at Fogo de Chao!
Tom becomes a faculty member in the Department of Biological Chemistry at UCLA. Check out his official profile page!.
The lab participates in the LA Cancer Challenege 5K/10K!
(Liz – 1st place female age division; Bethan – 3rd place female age division)
Tom receives the David Williams Lectureship award at the Kern Lipid Conference 2016.
Tom and Liz welcome Bethan Clifford, Ph.D., a post-doctoral fellow from England to the lab.
Our latest lab member joins! Elinor Lee, M.D. who is in the STAR program at UCLA. Elinor will do her PhD in the lab focusing on lung lipid metabolism!
Tom receives his first NIH R01 from the NHLBI.
Tom presents his latest work, with fellow ATVB Council members at the Brazilian Atherosclerosis Society meeting in Campos do Jordao, SP, Brazil.
Tom wins the Irvine Page award from the AHA.
The lab publishes our latest work in Cell Metabolism!
Tom and Liz welcome baby Olivia to the world.
Liz receives an NIH K99/R00 Pathway-to-Independence Career Development Award.
Tom and Liz become Assistant Professors in the Department of Medicine, Division of Cardiology at UCLA!
