Latest news!

What a way to round out 2021. Tom is named the Home Area Director for the MBIDP Gene Regulation, Epigenetics and Transcriptomics graduate home area in the UCLA Graduate Programs in Bioscience! Congratulations Tom!

We continued our annual tradition of our Deck The Halls Lab Contest. This year we shook things up a little and challenged lab members to create a decoration that we can hang on our new Lab Christmas Tree. Check out our tree and this years' entries, runners up and overall winner!

Tom presents some of the lab's newest and greatest research at the UCLA Cardiovascular Theme Symposium, our first in-person event in almost 2 years!

We are super happy and exicted that Gabriella Rubert has decided to join the lab as a Ph.D. student! Meet Gabriella here .

Excited to get the Notice of Award for (can you believe it) the first MPI R01 for Liz and Tom!

Another publication with our Australian Collaborators! Great to see this continuing despite the global pandemic!

Congratulations to ETV Alumni Tim Yu on another paper published!

Excitement in the lab to get the first shots of our COVID-19 vaccines!

Congratulations to the lab for their Christmas Decoration entries! We were selected as one of the winners of Addgene's #DeckTheLab contest! Can't wait to see what our prizes are!

Congratulations to Research Fellow Alvin for his latest research on dietary trends in the rare pediatric disorder glucose galactose malabsorption .

We are kicking off 2021 in style with the release of our new lab logos!

Liz, Tom, and Olivia welcome Baby Leo!!

Postdoc Leslie is awarded one of the first iCMB T32 postdoctoral training grants, bridging bioengineering and biomedical science! Well done Leslie!

We are very pleased and excited to welcome Gabriella Rupert as a Rotation student to Team CRISPR. Gabriella will working on designing guide RNAs to some of our newly identified metabolism targets.

We are excited to welcome Alvin Chan as a Research Fellow in Pediatrict GI. Alvin will be working on all things related to bile acids and absorption! Get to know Alvin here .

As COVID-19 continues to impact our research, we are happy to welcome rotation student Kelly Kennewick to the lab for a virtual rotation. Kelly is part of the IMMP home area in the GBP at UCLA and will be working with Liz on analyzing lipidomic and FACS data in mice with disrupted lipid and immune homeostasis.

This time we said Goodbye to Li, who is going back to NorCal to work in Industry. We didn't get to have a proper farewell thanks to Pandemic Restrictions and the Safer-at-Home order in Los Angeles, but we wish her all the best!

Along with many other labs and research campuses across the country, we made the difficult decision to shut down our lab in mid-March as COVID-19 began to rage and Los Angeles issued an emergency Safer-at-Home order.

We are desperately sad to be saying Au Revoir to our favorite baker/technician extraordinaire, Pauline, who is returning to her native France. The lab took to her beloved trails for a farewell hike, and we couldn't let her leave without baking just one more delicious cake!

Yet another publication, this time from undergrad Tim's previous lab. This is Tim's first first author publication and preprint where they built and tested 8269 variations of the classic lac promoter where we reposition and tune the strengths of binding sites. This study shows new interactions between binding sites and how to build theoretically optimal inducible promoters. Read this cool story about promoter architecture here .

What a way to ring in 2020 with not one, but two papers accepted from the lab! First, we performed silencing of microRNA-144 in pre-clinical models of atherosclerosis. Second, in collaboration with Jan Kornfeld, we discoverd a MAFG-lncRNA axis that links nutrient abundance and hepatic glucose metabolism.

The lab celebrated Thanskgiving with their annual Friendsgiving meal!

Today we celebrated postdoc Bethan and Kelsey's big summer birthdays!

Our undergraduate Rachel who has been working over the summer as part of the CARE summer research program, presented her research! Well done Rachel!

Today we said farewell to Postdoc Jenny Link, who is starting a faculty position at Whittier College. We will miss you and are very proud of you Jenny! Good luck in your next adventure!

Summer BIG students Tyler and Vivan present their work. Lots of fun talking science!

We were sad to say goodbye to Elizabeth Vanderwall at the end of this month. Elizabeth is moving home to Seatle before embarking on the next chapter of her adventures and applying to Grad School.

The lab made some furry new friends in what was possibly the best. day. in. lab. ever!

The lab made sure to document #nationalselfieday by cramming everyone into a very small space!

Liz gives a talk at the Gordon Research Conference on Atherosclerosis at Sunday River, Newry, ME!

Liz gives Medicine Grand Rounds with Dr. Tisha Wang discussing the progress they have made working on Pulmonary Alveolar Proteinosis!

Gloria, who has been in charge of our animal colony for several years, is promoted at UCLA. We celebrated with another delicious cake from Chef Morand! We wish Gloria all the best and we will miss her terribly!

Congratulations to Tom and Dr. Peter Edwards on being awarded an NIH MPI R01 to study FXR and liver lipid metabolism!

In collaboration with colleagues at the Baker Heart and Diabetes Institute, in Mebourne Australia, we performed a systems genetics analysis of mammalian lipid metabolism. Check out this report for more information.