JBelperio@mednet.ucla.edu
(310) 794-1992
John A. Belperio, MD is the Interim Chief and Professor of Medicine in the Division of Pulmonary, Critical Care, Sleep Medicine, Clinical Immunology and Allergy at The David Geffen School of Medicine at UCLA. Dr. Belperio completed undergraduate at Drexel University in Philadelphia with a B.S. in Chemical Engineering, Medical School at the Temple University and Residency training at The University of Maryland. He then completed fellowship training in Pulmonary and Critical Care at The University of Michigan. After fellowship he was recruited to the Division of Pulmonary and Critical Care Medicine at The David Geffen School of Medicine at UCLA and has served on faculty ever since. His research program has focused on the role of chemokines and cytokine during the pathogenesis of lung allograft dysfunction, interstitial lung diseases (i.e. Idiopathic Pulmonary Fibrosis and Sarcoidosis) and Obstructive lung disease (COPD/emphysema and bronchiectasis). His work in the area of CC chemokines has demonstrated that these proteins are key in recruiting specific populations of pro-fibrotic mononuclear cells to the lung allograft during allograft dysfunction and interstitial lung disease. His work on ELR- CXC chemokines has demonstrated their role in neutrophil recruitment and angiogenesis during chronic lung allograft rejection (CLAD) and Sarcoidosis. He also found that interferon inducible ELR- CXC chemokines were important in recruiting memory T cell to the lung allograft that eventually leads to CLAD. His work involves human samples in combination with molecular and cellular biology techniques, which are then brought to murine model systems to prove proof of concept that these proteins are actively involved in the above disease.
Assistant Professor
SWeigt@mednet.ucla.edu
(310)-794-1996
Dr. Sam Weigt is an Assistant Professor in the Division of Pulmonary and Critical Care Medicine. He is also the director of the Interstitial Lung Disease Center and Pulmonary Fibrosis Foundation Care Center at UCLA.
He is a graduate of Creighton University School of Medicine, where he earned his M.D. degree. He then did his residency training in Internal Medicine and fellowship in Pulmonary and Critical Care at UCLA. He earned his Master of Science in clinical research through the Specialty Training and Advanced Research (STAR) Program at the David Geffen School of Medicine at UCLA.
Dr. Weigt joined the faculty at UCLA in 2008. Dr. Weigt is an attending physician in the Interstitial Lung Disease Center, the Lung Transplant Program, and on the Advanced Lung Disease inpatient consult service at UCLA. Dr.Weigt is also an active researcher who studies interstitial lung disease and lung transplant rejection.
Associate Project Scientist, Step II
vpalchevskiy@mednet.ucla.edu
(310) 794-2020
Dr. Vyacheslav (Slav) Palchevskiy is an Associate Project Scientist, Step II, in Dr. John A. Belperio’s laboratory. He earned his B.S. degree in Microbiology and Molecular Genetics at UCLA (1999). He completed his Ph.D. in Molecular Biology at USC (2007), where he explored the role of exogenous DNA as a nutrient source for starving bacteria during competitive survival in environments containing limited nutrients.
Dr. Palchevskiy’s primary research is focused on exploring the role of T-cell biology during the pathogenesis of pulmonary disorders and rejection after lung transplantation. More specifically, to evaluate the role of chemokines and T cell interactions using heterotopic tracheal transplantation (HTT) and left lung orthotopic transplantation (OLT) murine animal models. In addition, Dr. Palchevskiy is actively involved in The Clinical Trials in Organ Transplantation (CTOT) multi-center study projects to evaluate the clinical risk factors and biological mechanisms for chronic lung allograft dysfunction (CLAD) pathogenesis.
Staff Research Associate III
WLung@mednet.ucla.edu
(310) 794-2008
Wing Yi Lung is a Staff Research Associate III in Dr. John Belperio’s lab. She has a B.S. degree in Microbiology, Immunology, and Molecular Genetics from UCLA. Prior to joining the Belperio lab, Wing’s research focused on examining how influenza infections alter immune responses against secondary bacterial infections, using a combination of in vivo and mice models. Currently, Wing’s research is focused on examining T cell subsets and associated chemokines in mouse models of pulmonary fibrosis, COPD, and pulmonary sarcoidosis. Crucial insights into the triggers and underlying cellular and molecular mechanisms driving the disease pathogenesis of these advanced lung diseases will be helpful for developing therapeutic and prognostic strategies.
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Undergraduate Student, Work-Study
(310) 794-2008
Undergraduate Student, Work-Study
(310) 794-2008
Undergraduate Student - Volunteer
(310) 794-2020
Assistant Project Scientist, Step I
ShahrzadLari@mednet.ucla.edu
(310) 794-8595
